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June Derick Reyes
June Derick Reyes Contributing Writer | FTP gacha games enjoyer
Best Gaming Mouse for Big Hands: 7 Mice for Comfort in 2025
Image credit: Amazon

Finding the best gaming mouse for big hands isn’t an easy task. Large hands need more space, a completely different shape of the body, and conveniently placed programmable buttons. Standard models often don’t consider these factors. As a result, gamers face cramps, fatigue, and missed shots at the most critical moments of the fps games.

This review features 9 models designed specifically for gamers with big hands. When putting together this selection, all essential aspects were taken into account: ergonomics, precision, scroll wheel, palm grip, long battery life, and high build quality.

If you’re looking for a wireless gaming mouse or a best wired gaming mouse, our list will help you. Here you’ll find the perfect gaming mouse for your style and hand size.

Why you can trust our advice

Eneba's writers and experts spend hours testing and reviewing games and gaming gear. Each review is based on hands-on testing, real-world use, and careful analysis. Our goal is to give you honest insights that will help you make the best decision for your setup. See how we test products.

Our Top Picks for Gaming Mouse for Big Hands

More and more computer peripheral manufacturers are now aiming to release most mice tailored to players with different needs. After reviewing player feedback and reviews, we highlight the following top 3 best models:

  1. Logitech G502 X Plus – best overall gaming mouse, model combines a comfortable ergonomic shape, optimal for palm grip and large palms. It has 13 programmable buttons and Lightforce hybrid switches.
  2. Razer DeathAdder V3 HyperSpeed – This wireless mouse weighs just 55g, is equipped with the Focus X 26K DPI sensor, offers up to 100 hours of battery life, and has up to 8 programmable buttons.
  3. Logitech G903 LIGHTSPEED – Features an ergonomic ambidextrous body, LIGHTSPEED connection with 1 ms polling rate, HERO 25K sensor with 1:1 tracking, sensitivity up to 25,600 DPI, and zero latency (perfect for shooters).

 So you can often easily find the best gaming mouse for large hands just for yourself, keep scrolling for more details and other options!

Best Gaming Mouse for Big Hands: 7 Ergonomic Mice Packed with Performance

Our selection includes 9 models perfectly suited for gamers with large palms. The list turned out quite diverse. From the best wireless gaming mouse with a lightning-fast wireless connection to ergonomic gaming mice with a comfortable thumb rest and advanced features.

Some devices are great for MMO gaming fans, while others appeal to those who prefer lightweight gaming mice for quick reactions in competitive gaming. Thanks to the variety of shapes, weights, and features, everyone will find the ideal gaming mouse for themselves.

Scroll through the list and pick your best gaming mouse for big hands, designed for comfort and maximum performance.

1. Logitech G502 X Plus [Best Overall Gaming Mouse for Big Hands]

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Logitech G502 X Plus Mouse on a white office desk positioned for photography
SpecsDetails
SensorHERO 25K
Weight~106 g
Buttons13 programmable buttons
ConnectivityLIGHTSPEED wireless connectivity (1 ms report) + wired USB-C
Battery LifeUp to 120 h (RGB off), ~37 h with RGB on
Dimensions3.1 x 1.6 x 0.1 inches
Mouse featuresLIGHTFORCE optical‑mechanical switches, PowerPlay charging compatibility, LIGHTSYNC RGB

Logitech G502 X Plus is an updated version of the iconic model, designed with a focus on ergonomics, precision, and maximum performance.

Right now, it’s one of the top Logitech gaming mouse options on the market. The HERO 25K sensor delivers flawless motion tracking with no smoothing or acceleration. With 13 programmable buttons, the latest LIGHTFORCE switches, and a dual-mode scroll wheel, the mouse is perfect for both esports and everyday gaming.

Why we chose it

The mouse combines cutting-edge technology, a comfortable shape for large hands, and top-tier precision, making it a universal choice for all game genres.

The versatility of this best gaming mouse stands out. The device works both wired and wirelessly via LIGHTSPEED with a 1 ms response time. It supports wireless charging through the POWERPLAY system, and the customizable RGB lighting adds style and adapts to gameplay.

ProsCons
✅Ergonomic shape fits large and medium sized hands perfectly

✅13 fully programmable buttons for versatility

✅Long battery life (up to 120h without RGB)

✅Dual connectivity: wireless and wired

✅Optical-mechanical LIGHTFORCE switches feel crisp

✅Compatible with PowerPlay wireless charging

✅LIGHTSYNC RGB adds premium style
❌ Slightly expensive, but the features fully justify the price

Final verdict: This mouse remains the gold standard for big hands thanks to its precise HERO 25K sensor, ergonomic shape, and versatile functionality. Suitable for both esports and everyday gaming, with PowerPlay support and RGB adding extra appeal for demanding players.

2. Razer DeathAdder V3 HyperSpeed [Best Budget Gaming Mouse for Big Hands]

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Razer DeathAdder V3 HyperSpeed Mouse on a white office desk with simple styling for a review
SpecsDetails
SensorFocus X 26K, maximum DPI up to 26 000, ~500 IPS, 40 G acceleration
Weight~55 g
Buttons8 programmable buttons
ConnectivityHyperSpeed 2.4 GHz wireless, 1 ms latency; optional dongle for 8,000 Hz polling
Battery LifeUp to ~100 h at 1000 Hz polling
Dimensions‎4.81 x 2.55 x 0.1 inches
ExtrasUSB‑C charging; ergonomic right-handed gamers design optimized for large palms, solid battery life

The flagship Razer mouse with an outstanding reputation among esports players. Ultralight, only 55 grams. It literally glides over the mousepad, delivering lightning-fast response and precise movements. 

Plus, this ergonomic gaming mouse is fully adapted for big hands. It features an extended body, deep palm rest, and perfectly balanced weight. The Focus X 26K sensor guarantees top-level accuracy up to 26,000 DPI, tracking at 500 IPS, and 40G acceleration. 

It supports HyperSpeed Wireless in the best budget gaming mouse, providing a stable and fast connection even at tournaments. And with the optional dongle, you can boost the polling rate up to 8000 Hz.

Why we chose it

Thanks to its weight, excellent battery life, and professional ergonomics, this Razer lightweight gaming mouse became the optimal choice for gamers with big hands, especially in genres where speed and precision matter.

Charges via USB-C, with a single charge lasting up to 100 hours of active gaming prowess. Inside are Optical Mouse Switches Gen 3 rated for 90 million clicks with no double-click issues or delays. Razer also added a pleasant soft-textured coating so your hand won’t get tired even during marathon sessions.

ProsCons
✅Ultra light weight makes (55g) yet durable

✅Ergonomic right-handed design for palm grip comfort

✅26K DPI Focus sensor for excellent precision

✅HyperSpeed wireless with low latency

✅Long battery life up to 100 hours

✅Compatible with 8K polling dongle for ultra responsiveness

✅USB-C fast charging
❌ No RGB lighting, but performance-focused design makes up for it

Final verdict: Lightweight, fast, and extremely comfortable for large hands, making it ideal for FPS and high-paced titles. Excellent battery life, ergonomics, and a 26K DPI sensor make it the best budget choice without sacrificing performance.

3. Logitech G903 LIGHTSPEED [Best Gaming Mouse for Big Hands – Unmatched Versatility]

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Logitech G903 LIGHTSPEED Mouse on a white office desk in close-up for a review
SpecsDetails
SensorHERO 25K 
Weight3.88 ounces
Buttons7–11 programmable (depending on side panel config)
ConnectivityLIGHTSPEED wireless, 1 ms report rate
Battery LifeUp to 140 h with RGB; ~180 h without
Dimensions‎1.59 x 2.62 x 5.13 inches
ExtrasAmbidextrous shape, removable side buttons, POWERPLAY wireless charging support

A multifunctional wireless gaming mouse from Logitech that’s hard to overstate. It’s perfect for both right- and left-handed users thanks to its symmetrical design and removable side buttons. Weighs about 110 grams (3.88 ounces). But the ergonomics here are simply flawless. The best ergonomic gaming mouse feels very balanced even during long sessions. 

The HERO 25K sensor in Logitech mouse delivers pixel-perfect precision. You get 1:1 tracking, 25,600 DPI, 400+ IPS, and zero smoothing or acceleration. It runs on LIGHTSPEED technology, providing professional-grade 1 ms wireless response time.

Why we chose it

Versatility, accuracy, and battery life make this gaming mouse the best choice for big hands, especially if you’re left-handed or just want absolute freedom in customization.

Up to 140 hours of battery life with RGB lighting or 180 hours without it. Just comfortable gaming with no compromises. And POWERPLAY wireless charging support completely removes any cable worries. Just place the Logitech mouse down, and it charges right during gameplay.

ProsCons
✅Ambidextrous design with modular buttons

✅Wide DPI range and high precision HERO sensor

✅Supports POWERPLAY wireless charging

✅Up to 140–180 hours battery life

✅7–11 programmable buttons with solid tactile feedback

✅Smooth wireless performance

✅Premium build quality
❌ Pricey, but unmatched versatility and build quality

Final verdict: A versatile option for both right- and left-handed users with modular buttons, long battery life, and flawless HERO 25K accuracy. Perfect for those who value maximum customization and seamless wireless performance.

4. Razer Basilisk V3 Pro [Best Gaming Mouse for Big Hands – More Buttons, More Domination]

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Razer Basilisk V3 Pro Mouse on a white office desk with soft lighting for a review
SpecsDetails
SensorFocus Pro 30K optical, up to 30 000 DPI, ~750 IPS, 70 G acceleration
Weight~95 g
Buttons13 programmable buttons, four‑way HyperScroll tilt wheel
ConnectivityHyperSpeed wireless (1 000 Hz; up to 8 000 Hz with dock)
Battery LifeUp to 150 hours on Bluetooth / Up to 110 hours on Razer HyperSpeed Wireless (constant motion at 1000 Hz) / Up to 32 hours with the Razer HyperPolling Wireless Dongle
Dimensions‎5.12 x 2.96 x 0.1 inches
ExtrasTilt‑scroll wheel, Razer Chroma RGB, compatible with Mouse Dock Pro

If you’re a fan of MMO gaming mice with tons of customization and like having as many buttons at your fingertips as possible, this model from Razer is made just for you. It features 13 programmable buttons and a cool four-way HyperScroll wheel with two modes. There’s free-spinning for fast scrolling and a tactile mode for precise control.

The Focus Pro 30K sensor in MMO mouse is not just accurate. It works brilliantly even on glass surfaces and offers DPI up to 30,000. Tracking speed reaches 750 IPS with acceleration up to 70G.

Connection via HyperSpeed Wireless provides ultra-fast, reliable wireless technology with a polling rate up to 1000 Hz, which can be boosted to 8000 Hz using the dock station.

Why we chose it

This is one of the most functional and precise models among most gaming mice, perfect for big hands and true MMO fans.

Battery life is impressive: up to 150 hours on Bluetooth or up to 110 hours on HyperSpeed Wireless, play long without recharging. The signature Razer Chroma lighting with 13 zones and over 16.8 million colors creates a full immersion effect, especially if you have a top-tier gaming monitor supporting RGB.

ProsCons
✅13 programmable buttons for MMO/FPS versatility

✅HyperScroll tilt wheel with tactile modes

✅Best-in-class Focus Pro 30K sensor

✅Multiple wireless modes including HyperPolling (8K)

✅Excellent battery life (up to 150h)

✅Dock Pro compatible

✅Premium Chroma RGB lighting
❌ Price is high, but features are future-proof and pro-grade

Final verdict: The perfect pick for MMO and multitasking gameplay — 13 buttons, HyperScroll wheel, and a Focus Pro 30K sensor give you total control. Designed for big hands, it delivers comfort and fast reaction times during long sessions.

5. CORSAIR Nightsword RGB [Best Gaming Mouse for Big Hands – Customize Your Grip, Command Your Game]

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CORSAIR Nightsword RGB Mouse on a white office desk with creative arrangement for a review
SpecsDetails
SensorPixArt PWM‑3391 optical, up to 18 000 DPI
WeightAdjustable 119–141 g
Buttons10 programmable
ConnectivityWired USB
Battery LifeN/A (wired mouse)
Dimensions‎5.08 x 3.38 x 1.71 inches
ExtrasSmart tunable weight system (real‑time center of gravity), RGB lighting, ergonomic thumb rest

If you’re looking for a versatile gaming mouse with maximum weight and balance adjustment, then CORSAIR Nightsword RGB is the perfect pick. This compact mouse, 130 mm long, features an exclusive Smart Tunable Weight system that tracks the center of gravity in real time and lets you adjust the weight. 

From 119 to 141 grams, creating a perfectly balanced tool tailored to your hand. At its core is a high-precision PixArt PWM-3391 optical sensor with resolution up to 18,000 DPI, adjustable in 1 DPI steps, ensuring perfect sensitivity and accuracy during gameplay.

Why we chose it

This multifunctional gaming mouse with unique weight and balance tuning is ideal for big hands and players who value comfort and precision.

The best wired mouse ergonomic shape with rubberized thumb grips delivers pro-level comfort. It’s great for long desktop sessions or paired with your best gaming laptop.

ProsCons
✅Adjustable weight system (119–141g)

✅Ergonomic thumb rest for long sessions

✅10 programmable buttons with good macro support

✅Highly accurate PixArt 3391 sensor

✅Smart real-time center of gravity tracking

✅Textured grip for better control

✅RGB zones customizable
❌ Heavier than average, but fully adjustable for personal preference

Final verdict: A mouse with a unique adjustable weight and balance system that fits perfectly to your hand. High precision and ergonomic shape make it ideal for players who value personalization and stability.

6. ASUS ROG Gladius III [Best Gaming Mouse for Big Hands – Swap, Click, Conquer]

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ASUS ROG Gladius III Mouse on a white office desk in a well-lit setting for a review
SpecsDetails
Sensor19,000 dpi with 1Percent deviation (specially tuned to 26,000 dpi), 400 ips optical sensor, and 1000 Hz polling rate
Weight~89 g
Buttons6 programmable
ConnectivityWired
Battery LifeWired
Dimensions‎4.84 x 2.68 x 1.73 inches
ExtrasHot‑swap Push‑Fit switches, PTFE feet, ergonomic right‑hand design

If reliability matters as much as precision, check out the ASUS ROG Gladius III. It uses a specially tuned optical sensor with 26,000 DPI and just 1% deviation. It delivers lightning-fast precision and smooth tracking with a 1000 Hz polling rate and speeds up to 400 IPS.

The main feature is the exclusive Push-Fit Switch Socket II, allowing you to swap mechanical switches and Omron optical microswitches without soldering. You can customize the mouse anytime to fit your needs. Plus, the durability rating of 70 million clicks is impressive.

Why we chose it

This mouse is primarily designed for serious gamers with big hands. It combines precision, reliability, and switch customization options.

The mouse has an ergonomic right-handed shape with a quality ROG Paracord cable and 100% PTFE feet with rounded edges for ultra-smooth gliding, especially on the right gaming mousepad.

ProsCons
✅Hot-swappable switch sockets

✅High-performance 26K DPI sensor

✅Excellent click feel and durability

✅Ergonomic shape optimized for right-handed users

✅Lightweight (89g) and comfortable

✅Responsive PTFE feet

✅Ideal for FPS gaming
❌ No wireless option, but wired precision is flawless

Final verdict: A reliable wired mouse with hot-swappable switches and a tuned 26K DPI sensor. Great for big hands and professional matches where stability and perfect response are essential.

7. HyperX Pulsefire Haste [Best Gaming Mouse for Big Hands – Honeycomb Speed & 100-Hour Battery for Marathon Gaming]

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 HyperX Pulsefire Haste Mouse on a white office desk with natural shadows for a review
SpecsDetails
SensorPixArt PAW3335, up to 16 000 DPI, ~450 IPS, 40 G acceleration
Weight~61 g
Buttons6 programmable
ConnectivityUSB wired (also wireless variant available)
Battery LifeN/A (wired); wireless version ~100 h
Dimensions‎4.7 x 7.1 x 2.4 inches
ExtrasHoneycomb shell, PTFE feet, HyperX Golden micro switches rated 60 M clicks, RGB

Another lightweight model is an excellent choice for those who want a balance between speed and comfort. With an ultra-light honeycomb-style shell weighing only about 61 grams, Pulsefire Haste lets you easily control movements without fatigue even during long gaming sessions.

The mouse features a PixArt PAW3335 optical sensor with up to 16,000 DPI and can track movements at around 450 IPS, making it very accurate. Reliable TTC Golden switches rated for 80 million clicks and low response times provide stable and fast actuation.

The wireless version offers up to 100 hours of battery life on a single charge, while the wired option provides minimal latency with a 1 ms response time. The Pulsefire Haste shell is IP55-rated for protection.

It comes with a grip-enhancing sticker and spare pure PTFE feet for smooth gliding on any gaming surface.

ProsCons
✅Lightweight honeycomb shell (61g)

✅HyperX Golden micro switches (60M clicks)

✅Great for claw or fingertip grip users

✅High accuracy PixArt sensor

✅100-hour battery (wireless version)

✅PTFE feet for smooth glide

✅RGB lighting without added weight
❌ Build feels less premium, but excellent for speed-focused gamers

Final verdict: An ultra-light design with a protective shell and excellent sensor makes it a great choice for long sessions. Perfect for gamers with big hands who want speed, accuracy, and durability.

8. Glorious Gaming – Model D 2 [Best Gaming Mouse for Big Hands – Lightweight Comfort for Big Grips]

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Glorious Gaming – Mouse on a white office desk prepared for testing shots
SpecsDetails
SensorGlorious BAMF 2.0, up to 26 000 DPI, 650 IPS, 50 G acceleration
Weight58G ±3g Variance
Buttons6 remappable
ConnectivityWired USB
Battery LifeN/A
Dimensions‎4.98 x 2.64 x 0.1 inches
ExtrasAdjustable debounce, onboard profiles, RGB, lift‑off tuning

This top-tier budget gaming mouse is designed for players with big hands who are looking for the perfect balance between quality and price. The Model D 2 weighs only about 58 grams, making it surprisingly lightweight and ultra-agile. Perfect for exciting PC games where lightning-fast reactions and pinpoint aiming in milliseconds matter.

Equipped with the advanced Glorious BAMF 2.0 optical sensor, offering up to 26,000 DPI. This guarantees pixel-precise accuracy and smooth movement, even in the most intense games. Tracking speed up to 650 IPS and acceleration up to 50G deliver top-tier responsiveness.

Why we chose it

This best overall gaming mouse is perfect for gamers with big hands who appreciate lightness, precision, and reliability. Its protected shell and long battery let you focus on winning without distractions.

Buttons rated for up to 80 million clicks ensure durability and maximum reliability. Among premium features are customizable RGB lighting, an ultra-flexible Ascended Cable that won’t interfere with movement, and feet made of 100% PTFE for ultra-smooth gliding on any gaming surface.

ProsCons
✅BAMF 2.0 sensor with 26K DPI and high-speed tracking

✅Lightweight yet solid build (58g)

✅Ergonomic for palm and claw grip

✅Adjustable debounce time for custom click feel

✅Reasonable price point

✅RGB lighting and lift-off tuning

✅Smooth PTFE feet
❌ Wired only, but ideal for fast-paced competitive gaming

Final verdict: Lightweight, ergonomic, and budget-friendly with a premium sensor and high durability. An optimal choice for large hands and competitive and fast-paced gaming.

9. Glorious Model D [Best Gaming Mouse for Big Hands – Ergonomic 68g Honeycomb Beast for Palm Grip]

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Glorious Model D Mouse on a white office desk in a clean setup for a review
SpecsDetails
SensorPixArt PMW‑3360, up to ~12 000 DPI, ~250+ IPS, 50 G acceleration
Weight~68 g ± 1 g
Buttons6 programmable
ConnectivityWired USB
Battery LifeN/A
Dimensions‎5.04 x 2.64 x 0.1 inches
ExtrasOmron switches (20 M clicks), ergonomic honeycomb design, RGB

Glorious Model D, the best lightweight gaming mouse, perfect for players with big hands who prefer a comfortable and secure Palm Grip. Weighs about 68 grams and features a unique perforated honeycomb design. Its lightness allows for hours of fatigue-free gaming.

The PixArt PMW-3360 sensor with around 12,000 DPI offers crystal-clear tracking and top-level reaction speed. A true find among the best MMO gaming mice and shooter models.

Why we chose it

This big mouse is especially well-suited for players using Palm or Claw grip. The Model D is an excellent choice among the best mice for serious gaming, providing top comfort and precision.

The Glorious Model D comes with an ultra-flexible Ascended Paracord cable that minimizes resistance and feels almost wireless.

ProsCons
✅Excellent palm grip support

✅High-accuracy PMW3360 sensor

✅Very lightweight at ~68g

✅Durable Omron switches (20M clicks)

✅Honeycomb ergonomic design improves ventilation

✅Smooth PTFE feet for agile movement

✅Affordable price for specs
❌ Lower DPI than premium models, but still perfect for most gamers

Final verdict: A classic lightweight mouse with excellent Palm Grip support and lasting comfort. Well-suited for big hands, delivering consistent accuracy across all game genres.


How To Choose the Best Gaming Mouse for Big Hands?

Choosing the right gaming mouse for big hands can make or break your gaming experience. Here are a few simple tips to help you find the perfect mouse:

1. Prioritize ergonomics and size

Big hands need a larger mouse with solid ergonomic support. Small mice often mean discomfort and unnecessary strain.

One of the top choices for MMO players is the Corsair Scimitar Elite Wireless.

2. Consider the mouse’s weight

While lighter mice make quick movements easier, some gamers prefer heavier ones for better control. The ideal weight often depends on your gaming style — for example, FPS players usually favor lighter models for faster flick shots, while MMO players might opt for heavier designs for added stability during long sessions.

Adjustable-weight mice can offer the best of both worlds, letting you fine-tune the balance to your preference.

3. Match the mouse to your grip style

Whether you use palm, claw, or fingertip grip affects which mouse suits you best. Gamers with big hands usually prefer a palm grip on larger mice.

Make sure the button layout fits your grip for quick reactions without awkward hand movements.

4. Check the button placement

MMO fans need extra buttons. Programmable buttons are a bonus, letting you customize without overloading your hand.

5. Don’t compromise on performance

Look for a mouse with a wide range of DPI settings and low latency, regardless of connection type. Avoid cheaper mice that cut corners on sensor quality or response time. That will only ruin your gaming experience.


FAQs

What is the best gaming mouse for big hands?

The best gaming mouse for big hands is the Corsair Scimitar Elite Wireless or the Logitech G502 X, thanks to their large bodies, precise sensors, and comfortable palm-friendly shapes.

Is a bigger mouse better for big hands?

Yes, a bigger mouse provides better grip, comfort, and reduces fatigue during long gaming sessions. It lets the hand rest in a natural position without curling the fingers, which improves precision and control. Larger models also offer better support for the palm and wrist, reducing the risk of strain over time.

What is the best mouse grip for big hands?

The palm grip is the most comfortable for big hands, as it evenly distributes pressure across the palm and reduces finger tension. This grip keeps the wrist in a neutral position, which helps prevent fatigue. Claw or fingertip grips can be used but often feel cramped with large hands.

What hand size is considered big?

A hand length of 20 cm or more from the tip of the middle finger to the wrist is generally considered big. Players with this size benefit from longer mice that match their hand proportions. Wider mice also prevent side pressure on the fingers, improving comfort during long sessions.

What is considered a big hand for a man?

For men, a length of over 20.5 cm and a width of at least 10 cm is considered large. This size requires a mouse with enough length and width to support the palm fully. Choosing the right dimensions improves both comfort and accuracy.

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June Derick Reyes

Contributing Writer | FTP gacha games enjoyer

I'm an average enjoyer of memes, movies, anime, manga, novels, and video games. One fateful day, I tried my hand at crafting a long-form fantasy novel for kicks and discovered my deep-seated love and knack for writing.

Eager to express my other passions, I then delved into entertainment journalism in 2021 and have written hundreds of articles since then for FandomSpot, HardcoreiOS, TheGamer, and TalkAndroid, helping anime fans find new series they’ll enjoy and tryhard gamers git gud in a variety of games.

I also LOVE gambling—er, playing all sorts of gacha games mostly F2P in my free time.